GaiaOnline, a popular social network that's anime oriented, should be a meme itself. M00t already mentions it under the "Rules of the Internet" page.
"In 2007, 4chan’s founder Christopher Poole, better known as moot, was asked about the rules during a question-and-answer session at ROFLcon. He claimed that they were invented by Gaia and they did not actually exist."
Plus, it gave birth to other notable memes, the most popular being Boxxy.
So, why not, I mean, it's going to be one someday, why not start now?