This is a reaction image, likely from 4chan, dating as far back as 2013. The earliest use I could find (I'm not good at finding this stuff) is this FunnyJunk comment from May 22, 2013, though Google Trends suggests it may have started a year earlier. However, the same graph shows a huge spike starting this month out of nowhere, coinciding with normies picking up the reaction image (though usually with a light red background instead of blue, further suggesting this is from 4chan as their images often have red or blue backgrounds to match the boards). In many cases, it serves a similar prupose to the Conceited reaction.
I believe this was the first popular example of the resurgence:
I also saw this featured on iFunny recently:
'Look Between X And Y On Your Keyboard' Becomes Viral Phrasal Template Meme On Twitter (X) And Reddit