23andMe
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About
23andMe is personal genomics and biotechnology company used, primarily, to help users find their personal genetic profile. Customers of 23andMe send their saliva to the company, who test the sample and return a genetic profile and information about the customer's ancestry.
History
23andMe was founded on April 27th, 2006 by Anne Wojcicki, Linda Avey and Paul Cusenza.[1]
The following year, the company launched its first consumer-based product for $999. Less than a year later, on September 9th, 2008, the company lowered the price to $399.
On March 12th, 2009, the company announced its Parkinson's disease research initiative.
On June 24th, 2010, the company makes several new genetic discoveries "for hair curl, asparagus anosmia, the photic sneeze reflex, and freckling."
Features
The company operates by users sending a saliva sample to the company. 23andMe returns results six to eight weeks later. These results show the user a range of information about their ancestry, particularly which reigions of the world their ancestors came from and more specific percentage of what ethnicity they are.
Highlights
In 2008, the company's consumer-based test was Time magazine's Invention of the Year. In their designation of the honor, Time[2] wrote:
"We are at the beginning of a personal-genomics revolution that will transform not only how we take care of ourselves but also what we mean by personal information. In the past, only élite researchers had access to their genetic fingerprints, but now personal genotyping is available to anyone who orders the service online and mails in a spit sample. Not everything about how this information will be used is clear yet -- 23andMe has stirred up debate about issues ranging from how meaningful the results are to how to prevent genetic discrimination -- but the curtain has been pulled back, and it can never be closed again. And so for pioneering retail genomics, 23andMe's DNA-testing service is Time's 2008 Invention of the Year."
In April 2017, the company surpasses 2 million geneotyped customers.
Deal With GlaxoSmithKline
On July 25th, 2018, the British pharmaceutical company GlaxoSmithKline (GSK) signed an agreement to buy a $300 million stake in 23andMe, beginning a four year-collaboration.[6][7] The purchase would give the pharmaceutical exclusive access to 23andMe's DNA database. In the press release, GSK said, "The goal of the collaboration is to gather insights and discover novel drug targets driving disease progression and develop therapies for serious unmet medical needs based on those discoveries."
GlaxoSmithKline's Chief Scientific Officer and president of research and development said, "We are excited about this unique collaboration as we know that drug targets with genetic validation have a significantly higher chance of ultimately demonstrating benefit for patients and becoming medicines."
Anne Wojcicki, 23andMe's CEO and Co-Founder, said, "This collaboration will enable us to deliver on what many customers have been asking for -- cures or treatments for diseases. By leveraging the genetic and phenotypic information provided by consenting 23andMe customers and combining it with GSK’s incredible expertise and resources in drug discovery, we believe we can more quickly make treating and curing diseases a reality."
Some raised criticisms about the sale, particularly in regards to the security of the data as well as whether 23andMe customers knew that their DNA would be used for private profit.[8] Peter Pitts, president of the Center for Medicine in the Public Interest, said, "If people are concerned about their social security numbers being stolen, they should be concerned about their genetic information being misused. This information is never 100% safe. The risk is magnified when one organization shares it with a second organization. When information moves from one place to another, there’s always a chance for it to be intercepted by unintended third parties."
The head of the division of medical ethics at the New York University School of Medicine, Dr. Arthur Caplan, said, "A lot of people paid money to 23andMe to get their ancestry determined -- fun, recreational stuff. Even though they may have signed a thing saying, ‘I’m okay if you use this information for medical research,’ I’m not sure they understood what that really meant. I’m not sure they understood that it meant, ‘Yes, we’ll go to Glaxo, and that’s where we’re really going to make a lot of money off of you.'"
Online, people criticized the sale, for many of the same reasons outlined by health and ethics officials (examples below).
A 23andMe spokesperson responded to the criticism:
When a 23andMe customer consents to participate in research, we clearly state that their de-identified data may be used to identify potential areas or targets for therapeutics development and to conduct or support the development of drugs, diagnostics or devices and may be done so in collaboration with third parties. Participating in 23andMe research is always voluntary and requires customers to affirmatively consent to participate. They can also choose to opt-out of our research at any time.
On July 31st, 23andMe announced an updated consumer privacy guidelines.[9][10] According to the outline, the companies will get "express consent" from consumers, who will have access to "access, correct, or delete their data, as well as a ban on sharing data with law enforcement agencies, insurance companies and employers without consent."
Related Memes
23andMe Results Parodies
As 23andMe grew in popularity, people began sharing their results online. On April 25th, comedian Mike Drucker tweeted [3] a parody of the results page. His genetic tests returned results that read, for example, "Historically Blamed for Everything 46.4%," "Snow goblin. -5 against fire 18.3%," and more. The post (shown below) received more than 80 retweets and 820 likes in one week.
Several days later, Twitter[4] user @PeterKelly25 tweeted a parody results page featuring the lyrics to the Meredith Brooks song "Bitch." The post (shown below, left) received more than 11,000 retweets and 48,000 likes in three days.
Over the next few days, people continued to share fake results for humorous effect (examples below, center and right).
On May 1st, 2018, Mashable [5] published a report on the emergence of the "memes":memes/memes/.
Search Interest
External References
[2] TIME – The Retail DNA Test – Best Inventions of 2008 – TIME
[3] Twitter – @MikeDrucker's Tweet?
[4] Twitter @PeterKelly25's Tweet
[5] Mashable – Announce your *real* genetic makeup with the 23andMe meme
[6] Reuters – GSK bets $300 million on genetics as CEO plays down break-up talk
[7] GSK – GSK and 23andMe sign agreement to leverage genetic insights for the development of novel medicines
[8] TIME – A Major Drug Company Now Has Access to 23andMe’s Genetic Data. Should You Be Concerned?
[9] Mashable – 23andMe and other home test companies pledge new privacy guidelines on using people's DNA
[10] FPF – Privacy Best practices for Consumer Genetic Testing Services
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Top Comments
ImYourAverageMemer
May 03, 2018 at 06:46PM EDT
Braneman
Aug 02, 2018 at 07:27PM EDT