Notes:

The Mr. Krabs Anchovies Meme started on February 19, 2015, when an image was uploaded to Cheezburger by the user Supernova6. The image came with a few examples that generally typify serious situations or things, or poke fun at serious faces.
The image itself came from an episode of the TV show Spongebob Squarepants. The second part of the pilot, titled Help Wanted, where the main character Spongebob applies for a job at the Krusty Krab restaurant. He is swiftly dismissed until the eatery's owner, Mr. Krabs, smells something fishy in the form of ravenous anchovies. The image is the face Mr. Krabs makes just after he smells the anchovies, and says the word dramatically, "…anchovies.".
The image examples and author's profile can be found here: http://profile.cheezburger.com/Supernova6/lolz