Nathan "Nate" Drake is an American treasure hunter, fortune seeker and action pro, and the playable protagonist of the Uncharted series. He believes himself to be the descendant of famous English explorer Sir Francis Drake.

Nathan "Nate" Drake is the fictional protagonist of the Uncharted video game series, developed by Naughty Dog. He is a playable character in Uncharted: Drake's Fortune, Uncharted 2: Among Thieves, Uncharted 3: Drake's Deception, Uncharted: Golden Abyss, and appears in the motion comic prequel series Uncharted: Eye of Indra. He is voiced by actor Nolan North, who influenced Drake's personality by ad-libbing segments of the character's dialogue.

Naughty Dog based Drake's appearance and personality on daredevil Johnny Knoxville, actor Harrison Ford, and the heroes of pulp magazines, novels, and films. To make him relatable, the character was outfitted in jeans and a t-shirt, and given an "everyman" persona; he is strong-willed, and often jokes and quips. The designers focused on giving him realistic reactions to his environment; for example, he stumbles while running, barely clears objects during leaps, and recognizes the absurdity of the situations in which he finds himself.

Nathan Drake has been called the mascot of the PlayStation 3 game console, and is increasingly identified with the platform. His design and personality have drawn comparisons to other video game and film characters, such as Lara Croft and Indiana Jones. Many reviewers have called Drake a likable and believable character, and have noted that he is a rare example of a physically attractive character who is not exploited by designers as a sex object.