Be careful: this meme overload video might give you something incurable.

This video of He-Man singing the 1993 song "What's Up?" was inspired by the G.I. Joe PSA parody series. It was originally shared as a downloadable file on the Something Awful forums in 2005.

A group of older gentlemen and ladies were presented several Lonely Island videos including YOLO and Like a Boss. They were not amused.

Doghouse Diaries compiled some of the biggest faux-pas in the Twitterverse and assigned a scoring system to assess the quality of a user's Tweets. Click through to see all of the categories and share your score in the comments!

This rage comic character is often used to express laughter or general amusement.