Notes:

Also some features that I couldn't fit into that small screen:

Hunger, Thirst (rip Pearl) , Sleep and Sickness added, basically what you expect from a survival liek mode.
(Sickness can be cured by visiting a doctor or taking antibotics)

In case it wasn't clear, you can't quicksave or manually save, if you want to save, you have to sleep in a bed/sleeping bag/mattress.

To get the Well rested bonus (which now gives you +2 Agility, +2 Endurance and 10% more xp), you need to sleep for at LEAST 7 hours, but it doesnt have to be in a special bed anymore but it HAS to be a bed. Mattress and sleeping bags cant give you the buff.

Console commands are disabled.

Carry Weight is reduced Drastically both to you and companions (example: With 6 Strength you start with 135 wt).

Stimpaks (NOW WITH WEIGHT), Radways and chems in general have negative effects when used (Stimpaks makes you more thirsty and radways makes you hungry AND tired, the latter removes well rested bonus).

Ammo has weight (a mini nuke weigh 12 pounds, 12 . ,Fusion cores weigh 4, missiles's 7. All others are around 0.029 or below. Except for freaking Shotgun shells which weigh 0.1 each )

In other news, this mode actually makes Leady Belly, a perk that 99% of players considered useless… pretty f------ useful, like h--------.