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Origin Entry: JoJo's Bizarre Adventure

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LOVE THE THIRD REICH look man he helped me through a very tough time so he means a lot to me okay you just gotta respect it (COOL)

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I made another unfunny dead meme)

SPOILER

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Rai Mamezuku: The Plant Appraiser

NSFW + SPOILER

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Jojo's Bizarre Hiatus

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Shampoo "The Miracles of the Flowers". Enriched with Jojoba.

Found in a Jojo's Facebook Meme page. Tried finding the original source, but no luck.

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Buon Compleanno GioGio!

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When you stopped time, but someone said "You're next!"

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I made this

色彩設計, 佐藤裕矛美術監 을 振影監督取編集廣瀬清志

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JJBA Great Days

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I can't punch you if I'm not close enough

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A jojo reference in a research paper..

ed and was grafted onto the TORCI nd slucose sensing mechanisms and how nutrient organisIns. in multicellular organisms. Here, we review ailability is cransduced to TORCI in yeast and mammals RAG GTPa ses and their upstream regulators ino acid sufficiency regulates TORC1 via different mechanisms largely involve the conserved RAG family of small GTPases (for v, see Jewell et al, 2013; Bar-Peled & Sabatini, 2014; payashi & Hall, 2015; Hatakeyama & De Virgilio, 2016; Powis irgilio, 2016; Fig 1). T ACC, and RACD) and two in S. cerevisiae (Gtr here are four RAGs in mammals (Schürmann et al, 1995; Hirose et al, 1998; 1). Mamm alian RA plex RAGULATOR (Sancak et al, 2010; Bar-Peled et al yeast, the EGO (Egol-Ego2-Ego3) ternary complex20 O RAGULATOR, tethers Gtrl/2 to the availability, by interacting with the lysosomal penta y Gs localize to the lysosome irrespective e exchange factors, res has been reported to inhibit TORU. essential TORC1 component Tco89 (Demetriades et al, (Gao et al, 2002; Kene al, 2003a; Dibble et al, 2012). Thus, full a yeast, the active Gtrl-P hete rson et al, 2002: 2002; Onda et al, 2002; Tee et al, 2002; Garami ctiva- but via a mechanism that Gtr1/2 is tightly regulated by co wis & De Virgilio, 2016; Fig The nucleotide binding status from amino acids and growth requires input rGtr2 heterodimer exchange factors) (for review to stimulate TORC1, but via a mecha ) yeast TORCI is Po n that of mammals since () yeast TORCI is east, rathe ed to the limiting membrane of the vacuole or orthologs. We note that yeast contains a 2009). The heterotrimeric ing TORC1) function as irrespective of the presence or absence a scaffold for the RAGS, has G or a nitrogen source (Kira et al 2014, et al, 2012). In y or a nitrogen source (Kira et al, 2014 , 2009) o15), and (i) budding yeast does not protein Vamó has been prop toward RAGs 1) and SEA Urano et al, 2000), that resembles RHEB, but B homolog i hat requires transloca- GATORI is composed tnr 5), NPRL2 (nitrogen p nrocess th

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Do re mi fa so NO CHI NO SA DA ME JO JO

Do Re Mi Fa So NO CHI NO SA DA ME JO JO

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We'll see each other again before the end...and remake ZA WARUDO

Jonathan's 150th birthday anniversary
*manly tears*

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+35

JoJo's Bizarre Adventure - Star Platinum punching a Minecraft tree

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Uploaded Apr 22, 2018 at 03:54PM EDT

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JoJo's Bizarre Adventure

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