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TMP-SMX mechanisms of resistance Reducedaug accumulation.via reduced membrane permeability and increased efflux.activity brug modufication/inactivation by enzymes 'Iarget site modification via mutatlons Fo DHPS, gene duplicatlans, or a plasmid with mutations in the TMP or SMX binding sites OVERVIEW OF ANTIBIOTICS •B-lactams: inhibut cell wall synthesis; bactencidal >Denicillins, cephalosporuns. Sulfonamides: prevent growth.and replication; bacteriostatic Prontosu, sulfadiazıne, suifisoxazole Aminoglycosides: inhibit protein synthesis; bactenadal Sreptomycin, neomycin, kanamyan, paro momycin ·Tetracycine : inhibit protein synthesis; bactenostatic →Tetracycline, doxyaycline, limecycine, oxytetracycine • Chicramphenicol: innioits protein synthesis; bactenostatic • Macrolides: inhibit protein synthesis; bacterostatic Erythromyciny. clanthromycin, azuthromycin. • Glycopeptides: inhubit ceul wau synthesis; bactericidal → Vancomycin, teicoplanin Ansamycins: innibit RNA synthesis; bacteriadal → Geldanamy un, nfamycin, naphthonycin al • Quinolanes: interfere with DNA replication and transcrptom, m →uprofloxaciny levofloxacin, trovafloxacin Streptogramins: inhubut protein synthesis; bactena" •Oxazolidinenes: inhibit protein synthesis; bact →Linezolid, pOszolid, tedizolid, cycoserir functions; bactenadal ·Lupopeptides:disrupt muetple cell me. Daptomyin sUi fou

I finished my last set of class notes for the term on the last line of the page, where my pen ran out on the last word | /r/mildlyinteresting


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Mildly Interesting - I finished my last set of class notes for the term on the last line of the page, where my pen ran out on the last word | /r/mildlyinteresting

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Uploaded Dec 08, 2019 at 10:46AM EST

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Mildly Interesting

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