Rapper NBA YoungBoy is at the center of yet another meme on TikTok as videos of people suffering from the mysterious "Baby Boo Syndrome" go viral on the app.

The videos are inspired by the wildly popular "She Gon' Call Me Baby Boo" remixes and focus on a particularly insane version of the remix trend that combines "What You Is" with Frank Ocean's "White Ferrari."

So, what is Baby Boo Syndrome, is it real and why is it going viral? Here's what you need to know.

@girlwithdaburger poor girl tiktok please find her @ #babyboo #nofriends #fyp #sadness #xyzbca ♬ original sound – kking

What Is The 'Baby Boo Syndrome' Meme?

NBA YoungBoy's song "What You Is" has been the subject of a lot of TikTok memes between late 2025 and early 2026. It started in September 2025, when a dance known as Babybooing went viral.

In January 2026, people began remixing the song with every other song imaginable to make the most absurd tracks possible, often by syncing and slapping the lyrics over another song's beat no matter how poorly they mesh.

Then in February 2026, as an extension of the remix trend, TikTokers started posting videos of themselves jittering, half-dancing and acting erratically as a remix of "What You Is" and Frank Ocean's "White Ferrari" plays. These jittering motions are known as "Baby Boo Syndrome."

@whosroyal2

♬ original sound – kking

How Is 'Baby Boo Syndrome' Used In Memes?

The Baby Boo Syndrome meme was purportedly started by TikToker @kkingmf. On February 10th, she posted a video of herself, filmed as if captured by a random onlooker, moving erratically at a lunch table under the caption, "Caught this girl with babyboo syndrome sitting alone."

From there the trend took off as other TikTokers posted similar videos. In many of the videos, the person with Baby Boo Syndrome is shown awkwardly Babybooing, as if the syndrome is forcing them to dance.

As the meme continued to go viral it got increasingly elaborate. One example is a fake news report that compiles many of the clips with footage of a news anchor talking about how Baby Boo Syndrome is taking over the U.S. Fortunately, Baby Boo Syndrome is not a real illness, just a meme.

@user2857012835698671 @charley #sad #nofriends #babyboo #depressed #sadness ♬ original sound – kking

What Are Some More 'Baby Boo Syndrome' Memes?

@dancemediaco baby boo syndrome has gone too far… 😔 @kking @CEO Of Big Backs 🍔 👑 @burger girl @yazimenz @aydenwest @big foot @ᴇɴᴠᴇᴇ @….hmmm.m #shegoncallmebabyboo #edit #sadtrend #trend #babyboovirus ♬ original sound – kking

@dabigback

♬ original sound – kking

@speechlesssisee

♬ original sound – kking

@e.jahhh Yall know how to treat this?#ejahhh #babyboo #sick #illness ♬ original sound – kking

---

For the full history of Baby Boo Syndrome, be sure to check out Know Your Meme's encyclopedia entry for more information.