This isn't an example of a single meme, but it is an example of how meme culture and use has spread from fun on the internet to Serious Business.
http://community.statesmanjournal.com/blogs/politics/2013/02/05/the-senate-republicans-offer-visual-interpretation-of-democrats-agenda/
The Republican Party in Oregon made a meme to criticize the Democratic-controlled legislature's agenda. The Democratic party then fired back accusing the Republican party of trying to astroturf memes.
Is this the future of our nation's political debate?