So I ran into this issue specifically when uploading this image. Like a large number of drawn images that are posted for years on 4chan as reaction images, the original has a light blue background. When I was wanting to upload it I was thinkning it might be more useful for some people if it was instead transparent, and given that the background is solid blue, this is pretty easy to do. However, this sorta brought up and issue in my head.
Know Your Meme is a site meant specifically to document online internet culture. This kind of editing is technically a 'perversion' of this.Likewise, there are other memes that I have uploaded that I have modified from their original version. Sometimes when text was misspelled I edited the image to correct it. If the image was poorly edited/low quality (by accident or laziness, not deliberately like deep frying) I might go back and clean it up a bit, and/or use something like Waifu2x so it isn't as painful to look at.
I don't think this is a really big issue for most (I am pretty sure most would rather see the same meme slightly improved visually than the original one of poorer quality) but technically this is editing it from how it was originally. I don't know if something like this would rub people the wrong way.
The only time I could really see this becoming a real issue IMO, would be for the original image that spawned a meme. In this case, I can see value in preserving faults in the original upload. Most of these will end up being modified (onsite or elsewhere) into relatively high quality blank templates anyways.
I guess, while I get that it's extra work, so I certainly don't expect it to be a 'rule' to follow, are there objections to modifying images for uploads if they are just to improve quality?
Also, uh… would there be any interest in essentially the reverse? I've been working on editing some memes into discord emotes. This generally is making transparent small square images. While they are generally relatively good for the size they are.. there are not going to be all that useful for anything else. Just curious to see if there would be any interest in them.