Brotein Shake: This classic viral video has accumulated over 11.8 million views since its YouTube debut in May of 2008.

Brotein Shake: This BodyBuilding Forums member was humiliated in one of the most epic photoshop threads of all time, only to return years later with an impressive physique.

This face was created by Cheat Engine forums user Chris Farral in 2010 as a reaction face before being imported into rage comics.

E3 Memes: We can't talk about memes from E3 without talking about Takayuki Nushida, a Japanese interpreter who was so immersed in translating with his pen and notepad that it almost seemed like he didn't care at all.

In celebrating the anniversary of Sad Keanu, check out the third installment and the most notable spin-off series of the Keanu Reeves photoshop saga in 2010.