Tamifluriver Sisters

Tamifluriver Sisters

Part of a series on Touhou Project (東方Project). [View Related Entries]

Updated Dec 29, 2013 at 02:15PM EST by mona_jpn.

Added Oct 19, 2011 at 12:00PM EDT by mona_jpn.

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Tamifluriver Sisters (Japanese : タミフルリバー三姉妹), occasionally called X on drugs on YouTube , refers to a style of hand drawn animations featuring raging dance and eccentric action by cute characters as if they’ve taken Tamiflu[1], the antiviral drug for flu which was famous for an abnormal behavior of children who took this drug in previous.

Many characters from anime, manga and video games has been showing this aggressive dance in the videos on the Japanes video sharing service Nico Nico Douga (NND).


The triggering video of this fad “Three Tamifluriver Sisters” was posted to NND in December 25th, 2009 by user Tsunamayo (ツナマヨ).[2] This video has been watched about 1 million times on there.

Those three girls are Prismriver sisters[3] from Touhou Project series, and the song in this video is Rapid Ensemble, the arranged song of those girls’ theme music “Phantom Ensemble” from the Japanese doujin circle COOL&CREATE’s 2004 album Touhou Strike.[4] Because their raging dance reminds an abnormal behavior by Tamiflu which was a trending topic in those days, this video was entitled “Tamiflu-river” as a pun for this drug and the family name of those sisters.

In addition, one of the features of this video is its later part reproducing many kind of fads/memes on NND in the same vein to Raging X. The number of its sources is 28, and those are including Hampster Dance, Ran Ran Ru, Get Down, Crazy Frog Brothers, Caramelldansen, Po Pi Po, Danjo, Paffendorf Dance, Soaring Dance, Usatei, smoooochen・∀・, Overdrive, Shift Change RED_ZONE, etc…

Here is a comparison video with the originals.[5]


This video got much attention among NND users and some of them began following its style and creating their own “Tamiflu-river” videos around the begenning of 2010.[6] As well as animated videos, illustrations were posted to pixiv, a Japanes social network service for illustrators.[7]

Though the amount of creations of this series isn’t so many, “Tamifluriver Sisters” has been one of the popular subjects for the works of amatuer illustrators and hand drawn animators.



Touhou Project タミフル猫三姉妹[8] | ONE PIECE 【ワンピース】 タミフルリバー3船長[9]

Megaman 【手描き】タミフルナンバーズ三兄弟【ロックマン】[10] | Dance Cover カポエラ星人で 「タミフルリバー三姉妹」 踊ってみた[11]

For more videos, check out the videos section in this entry.


Some dozens of illustrations related to this series are uploaded to the Japanese social network service for illustrators pixiv.[12]

Search Interest

External References

Editor’s Note: Registration is needed to browse the original videos listed in this section.

[1]Wikipedia – Oseltamivir

[2]Nico Nico Douga – タミフルリバー三姉妹 / Posted on 12-25-2009

[3]Touhou Wiki – Prismriver Sisters

[4]Touhou Wiki – 東方ストライク

[5]Nico Nico Douga – 『タミフルリバー三姉妹』元ネタ(とか)と比較してみた / Posted on 12-31-2009

[6]Nico Nico Douga – Search results for タミフルリバー三姉妹

[7]pixiv – Search results for タミフルリバー三姉妹

[8]Nico Nico Douga – タミフル猫三姉妹 / Posted on 02-22-2010

[9]Nico Nico Douga – タミフルリバー3船長 / Posted on 12-08-2010

[10]Nico Nico Douga – 【手描き】タミフルナンバーズ三兄弟【ロックマン】 / Posted on 09-21-2010

[11]Nico Nico Douga – カポエラ星人で 「タミフルリバー三姉妹」 踊ってみた / Posted on 01-29-2010

[12]pixiv – Search results for タミフルリバー三姉妹

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