Astley's song and music video for "Never Gonna Give You Up" have become forever cemented as a cornerstone of internet history.

Zalgo was a bringer of destruction and doom and would appear in webcomic edits.

It started on Twitter, and from there threw hands across the web.

There have been a lot of quotes from adult movies to go viral, but none have had quite the power of "Right in front of my salad."

The American actor is well-known for his roles as popular villains, but in recent years, Dafoe has become the subject of numerous memes.