The Last of Us Part II - Abby's muscles before and after

They've also made her face less feminine as well.
No wonder they've compared her to Senator Armstrong.

You're right about Blazkowicz, but Venom Snake was actually pretty damn skinny, especially when you compare him to when after he gets fit again. Look at those noodle arms

Granted, he wasn't a skeleton or anything, but given that the doctors were performing all sorts of operations on him, you'd figure they tried to keep him as physically fit as possible.