It would end up between Dale and Flanders. Behind the religious humility and squeaky clean demeanor, Flanders is ripped and does have a breaking point. Certainly not a man you would want to piss off and face all that pent up rage.
Dale, meek as he is, is usually armed to some degree due to his paranoia. Even without a weapon, I think he can still be a scrappy in a fight with his underhanded tactics ala pocket sand and squirrel tactics.

Flanders? Peaceful?