Episode 8 of Lucky Star, "Energetic Despite Not Being Myself", premiered on May 27, 2007. It featured one of the main characters, Tsukasa, poorly playing a recorder in one scene of the show. Sometime in 2008, youtubers began to match this scene up with Tsukasa playing songs from video games and other works of famous in nerd culture. The most viewed video in this meme is Tsukasa play Dr. Wily's theme from Mega Man II:

The music form the ocarina of time is another popular choice for being edited into the video:

Dark Side of Fate, Hina's theme from Touhou (This one is new. This meme could be trending upwards).

The Star Wars Cantina Theme

Another video:

I was wondering if maybe if this meme can't stand on its own if all of the Lucky Star memes could be merged kind of like how all of the Gary Oak memes were put in one article.