AI Rat diagram from frontiers journal.

AI-Generated Rat Anatomy Illustration

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Updated Feb 19, 2024 at 02:13PM EST by Zach.

Added Feb 16, 2024 at 08:17AM EST by sakshi.

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Overview

AI-Generated Rat Anatomy Illustration, also known as AI Mouse Stem Cell Diagram or AI-Generated Rat Balls Pass Peer Review, refers to discussions, jokes and memes about the peer-reviewed science and technology journal Frontiers publishing a stem-cell research-related paper that used AI-generated diagrams and charts. Scientists and other users on the internet shared images of what appeared to be an anatomically inaccurate cross-section of a rat alongside equally incomprehensible charts and cell diagrams on February 15th, 2024, criticizing Frontiers for publishing the paper.

Background

On February 13th, 2024, researchers Xinyu Guo, Liang Dong and Dingjun Hao from the Department of Spine Surgery in Hong Hui Hospital and Xi'an Honghui Hospital published a peer-reviewed paper titled, "Cellular functions of spermatogonial stem cells in relation to JAK/STAT signaling pathway," in Frontiers.[1]

On February 15th, X[2] user @DrCJ_Houldcroft then made a post citing images from the paper, saying, "Erm, how did Figure 1 get past a peer reviewer?!" The post gathered over 9,000 likes in a day (seen below).


Dr CJ Houldcroft @DrCJ_Houldcroft Erm, how did Figure 1 get past a peer reviewer?! frontiersin.org/articles/ 10.33... H/T @aero_anna senctolic stem cells dielocttal stem ells Rat Testtomcels ALT Dissilced 7:50 AM Feb 15, 2024 3M Views dck- Retat iollotte sserotgomar cell Spermatocial stem cells : Stem cells

Also on February 15th, X[3] user @cliff_swan posted more images from the paper, writing, "Article published a couple of days ago. Every figure in the article is AI generated and totally incomprehensible. This passed 'peer-review.'" The post gathered over 50,000 likes in a day (seen below).


senctolic stem cells dielocttal stem ells Rat Testtomcels Dissilced dck Retat 2 - iollotte sserotgomar cell Spermatocial stem cells Stem cells 4- 3 M NIA&STA-ST TSAK 3 Signal briding the recetein Regestion Imm Seenimer Juk Regsttes AK C ARCRMS 0:00 10:00-1 Jheo STA Sims Jam JAK Sigal molecule SK 3AT Sinkecter JA JIKMA JAK Resprouization of le regisor JAK JAK SHIGE JAK HATEE JAK wwwwwwwww 000 00 Crong fo 3 Tramioncatiion of zxepens 1: Stats peflecation JAK Accrivetton and Jimde SA பயா OOT DODON CNMS TAT Proprounization Stat protemns STT (11 DMmer ragrogatio of fomens STAT DT 101 20 20 20000 2000 WODY / COM 5 Dimimeriom eme 5 Translocation <-2 -prom SKATSTAG
kab girduly Speedd angelay Semall Aprese Cmimotom Semtorid wall Spermatgolial scells sanallint on cthe jcike Spermakonial stat eanbing retecactint the nelnblion Sapimotostic enens pimtios Chemochactial moncele one in j-oakStart patray play Akrand Apvy 14 A Chermotaxis & stat homing Avas FIGH Sepmatocicial cell hormengennctiation Neemcticvatic ret enetinc simar acty cell mbiratio ammosite nice. Spacogtic sstem cells unde limcuce of the JAK pathrway D Spectagial als seme col MAN akhe saral selenesartial Jeste Spermagonial stamerts cells siglannellion Macromagues JaBuM cille Jay Vells sguinenme B AMrognec Macprahges Jermacgoli stem polay Sprination magan www #Troton Spernatagotial differfitatie infilucenced inter the sinaling pathway Spermutial stem cells Spenutoglals stem al 300 permalind some of IMMOUMINOMUDUODIUILATIUCIATON Sporamul Spepatalast Spermatsgotas cell cendudounte ssining enucls Jaky/Stat sienaliog-pogy Spematgonial stemp cell acignolicnu.. Ja-Celceb T-Cells nokollas Ingrim mrology signarg poloclay C E


The paper was also posted to the subreddit /r/LabRats[4] on February 15th, 2024, where it gathered over 1,600 upvotes in a day.

Developments

Following the backlash, Frontiers[8] issued an "Expression of Concern" followed by a retraction of the paper on February 16th, 2024 (seen below).


Cellular functions of spermatogonial stem cells in relation to JAK/STAT signaling pathway 1 2 Xinyu Guo¹ Liang Dong² Dingjun Hao¹* Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, China Department of Spine Surgery, Xi'an Honghui Hospital, Xi'an, China A retraction of this article was approved in: Retraction: "Cellular functions of spermatogonial stem cells in relation to JAK/STAT signaling pathway" Read retraction > An expression of concern on: 'Cellular functions of spermatogonial stem cells in relation to JAK/STAT signaling pathway' by Guo X, Dong L and Hao D (2024) Cellular functions of spermatogonial stem cells in relation to JAK/STAT signaling pathway. Front Read correction >

Online Reactions

On February 15th, 2024, X[5] user @SynBio1 wrote, "Somehow my reviewers always needed 3 months of convincing about the choice of Kruskal–Wallis versus Wilcoxon Rank-Sum as the test of statistical significance for supplementary figure 7j but giant AI generated rat balls just sails right though sure why not." The post gathered over 3,000 likes in a day (seen below).


Jake Wintermute @SynBio1 Somehow my reviewers always needed 3 months of convincing about the choice of Kruskal-Wallis versus Wilcoxon Rank-Sum as the test of statistical significance for supplementary figure 7j but giant Al generated rat balls just sails right though sure why not Dr CJ Houldcroft @DrCJ Houldcroft. Feb 15 Erm, how did Figure 1 get past a peer reviewer?! frontiersin.org/articles/10.33... H/T @aero_anna senctolic stem cells dielocttal stem ells Rat Testtomcels ALT Dissilced 11:21 AM Feb 15, 2024 225.5K Views dck- Retat iollotte sserotgomar cell Spermatocial stem cells Stenm cells

Many researchers joked about the diagrams, such as X[6] user @gramnegativity on February 15th writing, "I hate when I’m a Cmimotom minding my own business and then Spacogtic sstem cells unde limcuce of the JAK pathrway." The post gathered over 1,000 likes in a day (seen below, left).

On the same day, X[7] user @molbiomarie wrote "an exclusive look at my next paper 🧵," alongside a nonsensical AI-generated diagram of what appears to be a brain stem. The image gathered over 1,000 likes in a day (seen below, right).


Lauren Shull @gramnegativity I hate when I'm a Cmimotom minding my own business and then Spacogtic sstem cells unde limcuce of the JAK pathrway Spermatgolial scells sanallint on cthe jeike Spermakonial stat eanbing retecactint the neinblion Cmimotom Sapimotostice enens pimtios Chemochactial moncele one in joakStart patray Chermotaxis & stat homing 11:49 AM Feb 15, 2024 60.6K Views Sepmatocicial cell hormengennctiation Neemcticvatic ret enetinc simar'acty cell mbiratio ammosite nice Spacogtic sstem cells unde limcuce of the JAK pathrway Michael Baym @baym. 22h The authors may think they aren't being dishonest by citing Midjourney for these figures, but they are implicitly lying to the readers. One assumes in a paper (even a review) that the figures are made with thought, to convey an idea or argument. Whatever the prompt, this doesn't x.com/emselor/status... : D Jenna Harris, PhD @molbiomarie an exclusive look at my next paper poptecteracion Lechennation al Seys-nnopond patopectemation Senancals 1 nectliia IKL Neyouial раrеnнде LATAP CRED- Synenattion ALPA- 2 Lasesumge AM popoecatus APPEU -LmpOD -LAMRP peson -blipongenener NB Gairennte resslernd PONCUOll Learonning dermmcstia TP Calidude estcentation Galloe -CMBB-ND NcIMAlda irfflus ollu Fuon inccatum AP-Catono FFI DP clomo rmio SP ALS Clagcuon sliainig Gqoecrion -P. NLA Sayiation IILPA Mude minnwa) Hte aunótinalo polcenttiain peepeloine CAMKAIN Gluie -plaxe- LIN-O-O- Long-term potaticaality Pomeesod logic nioneim cludomitalte comumonnoson to nerneclitys LARAR Gliglun of arioin CAMRA 5:50 PM Feb 15, 2024 78.2K Views AKP CPEB > AMPP hun Ish Cacuum A IFM lonnd sinning Long-term and peperation Leaucouscleriat ace Grapbrion LLPA Caliniom resaronis gonniieal peplisa ماه - rocontis asioctal, guntcle ennnt moniciahton procemns LAME ga NOP-> Dunpation Penpestion sinnpion AMPP CREBB LAKA CMPhon CRD- -Clerwena emhmrabe secknouion Glupanation Sygnoapotenruation PHisenniorand nearmorl PPP-CREMA Cameemssnnaiepality lebebratcion Caclosunnain sallion www CAMB ROEKIO : MOPFF salling LNDDI/Camnly desamion Seytation istrun -Caloaguun dopiutins Caplume -Calicun orion Doineessaion porecsiors

Search Interest

Unavailable.

External References

[1] Frontiers – Stem Cell

[2] X – DrCJ_Houldcroft

[3] X – cliff_swan

[4]  X – labrats

[5] X – SynBio1

[6] X – gramnegativity

[7] X – molbiomarie

[8] Frontiers – Retraction

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Top Comments

Nox Lucis
Nox Lucis

Really doubles down on that alternate reality non-Euclidian body horror aesthetic.
But more seriously, the peer review process can only be as strong as a collective's dedication to the truth, and it seems clear to me that global society is moving towards a culture that doesn't see any moral value in truth. Expect science and data to get shakier moving forward.

+3

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