The comic came out in 2016 but memers are keeping it fresh, with multiple new renditions of the format hitting big on Reddit this past year.

WikiHow delivers with another inexplicable meme format, which features an old man brandishing a knife and a mustachioed gentleman cowering in fear.

Relatable sad moments from TV and video games + an exploitable webcomic = a meme goldmine once again with this all-too-relatable format.

With viral meme hits like 'Carl Wheezer Sings Slow Dancing In The Dark' and 'Zerwee' Billy Cobb blurs the line between meme and music, pushing the boundaries of both and making truly hilarious content.

The surprised face of a boy in class may be a relatable reaction image, but it comes from a horrific source.