I think the "Nanomachines, son!" of Metal Gear Solid V: Ground Zeroes has been found. It's a quote that's so obtuse in the middle of such a serious scene that it was only a matter of time before people started making fun of it.
I've seen users from a lot of Metal Gear fansites and video game sites make fun of both the line and the delivery. Tumblr is having a field day with this, for instance. Here are some of the many examples of the phrase used in text posts, not counting other content. In addition, there are quite a few pictures and videos on the subject, which I'll post after the jump. The only concern that I have about this is that the game has only been out for less than a month, and writing a page on this might be jumping the gun.
Anyway, here are some pictures and videos I found of the joke.
