http://funnyjunk.com/funny_pictures/2099841/That+means+you+re+gay/
The comic above is the origin of the reaction face. I know this isn't fully developed yet, but so far it has spread like wildfire on funnyjunk, and the users on fj will surely spread it to other sites. The reaction face is in the very bottom of the comic. I think this has potential and I'll be following it. If I get enough info I'll make an article.