"while looking out the window one day, a 1 megaton nuclear bomb detonates 30 miles from your house. The flash destroys your retinas and renders you permanently blind. You live downwind from the explosion. What do?"
I guess I'd have to rely on my family to get me to safety. There's a nuclear fallout shelter not too far from where I live, so I assume we'd go there. As for what to do afterwards, well being blind would obviously stink, but there's also the explosion to think about. Is it the result of some freak accident, or is there a nuclear war going on? If it's the former, I suppose we'd have to wait to be rescued by a special operations team or something. If it's the latter, I guess it doesn't really matter what my family and I do, since we'd be pretty much screwed now matter where we went.
Another scenario:
A mad, power-hungry dictator comes to power and asserts his rule in the area where you live. He claims to control the entire planet. His forces are technologically advanced and are well-organized; in fact, the entirety of the dictator's forces are made up of machines. Everyone you know except for a few of your friends have been arrested and their whereabouts unknown. You and your friends have managed to escape the dictator's forces and have been hiding in the forest for the past couple of days. You all know that you have to save your families, but your friends aren't certain where to start. What do?