Loss can be anything. Including a parody of itself! It is the ultimate meme. You may not find it funny, you may find it annoying, you may be sick of seeing it everywhere already. But it is so incredibly versatile and so fucking omnipresent that I don't think there is any competition. I mean, the only thing to be so widely spread that comes to mind is rage comics, by they are so ancient at this point.

This comic doesn't only make fun of "loss", it is also "loss"