Origins

The clip of Penn loudly exclaiming 'shut the fuck up!' is taken from a video from Penn and Teller's 'Bullshit!,' a documentary series about debunking paranormal myths and other phenomenon. Though the exact date origin for the video is not known, the earliest found was mid-2007, which was uploaded by a user named Jetsetlemming. It has received over 700,000 views.

Variations

A few good variations of the original video include a Sparta remix:

Another popular variation which was removed as the user was suspended, is a video entitled 'Penn Fucks his Break', in which the clip is synchronized into the Mega Man theme song. However there are parodies of the original parody such as this:

This is getting Penn Roll'D:

Up the Shut Fuck

Pu Kcuf Eht Tuhs

Fuck the Shut Up!

Fred Parody

In addition many ytmnd parodies have been made.

Popularity

A majority of the original videos have received over 30,000 views. A search of 'shut the fuck up penn' is in almost direct correlation (dates) to when the most popular variations of this video were uploaded.

In addition, search 'shut the fuck up video' has a Penn 'shut the fuck up' video as its first link.

Future

The search trends suggest that it's revived to some extent, and a few parodies have been posted in the last year. This one might still be unfolding.