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Splatoon was released on May 28th, 2015. In the game, the Inklings make various, nonsensical noises, popular examples of which have been identified by fans as "Woomy," said by female Inklings, and "Ngyes," said by male Inklings. One of the earliest parodies to utilize the "Ngyes" sound effect was posted on July 22nd, 2015 by user Cixia Volts, gaining over 44,000 views (shown below).
Over the following several years, the "Nyges" sound was utilized in numerous remixes on YouTube. Some popular examples include a post by GG Gabriel Gaming on January 1st, 2016 that gained 44,000 views (shown below, left) and a March 21st, 2017 post by MλNSTER TλPOUT that gained over 58,000 views (shown below, right).