Notes:

Some context might be in order:

"Appelbaum Syndrome is an extremely rare condition first documented a little under a century ago. Little is understood about this disorder as the only victims are psychic pokemon, whose unearthly abilities in themselves are barely understood to this day….
…Apple Syndrome is characterized by the pseudo-physical manifestation of a person or pokemon, visible only to victims of the syndrome, but capable of interacting with the world, an in advanced cases, possess entire personalities of their own…
…Various anti-depressant medicines have had limited success in treating the condition, though the side-effects range from…
…Due to this, rates of depression and suicide among sufferers are among some of the highest in the world."