Notes:

. Description
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A screenshot of two comments left under a 'What sin do you relish the most' meme.

. Explanation – This Series of Memes
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The 'What sin do you relish the most' memes feature Squidward, as well as a blue fish who was ordering food in the original scene from the cartoon show 'SpongeBob Squarepants'. In them, Squidward asks the fish which sin they relish the most, the fish replies (almost always with one word), and Squidward says "How" followed by an adjective. The fish then tries to justify/rationalize, or glorify the sin that they themselves mentioned, only for Squidward to speak ill of the sin, and possibly even the fish himself. Squidward will often make bleak assesments of the fish's fate, believing that the sin will harm or destroy them.

. Explanation – The Meme Itself
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One comment present in this screenshot mentions that the commenter struggles with overcoming their own sins. Specifically, sloth, lust, and wrath. They then ask God for forgiveness, and then call themselves "retarded".
For some reason.
Another commenter says that they think that they should just kill themselves.