Japanese users have Mikuru Beam, Ichiro Suzuki and DOOM series, while English users have Shoop Da Whoop.
Japanese users have Vocaloids while English users have Auto-Tune.
Japanese users have Toei Spider-Man while English users have '60s Spider-Man.
Japanese users have Miyoco while English users have Peanut Butter Jelly Time.
Japanese users have Billy Herrington while English users have Moar Krabs / Morbid Krabs.
Japanese users have Yaranaika? while English users have Morbid Squidward.
Japanese users have Automatic Mario while English users have Mario Paint Songs.
Japanese users have Suneo’s Bragging Theme Song Remixes while English users have Guile's Theme Goes With Everything.
Japanese users have pixiv while English users have deviantART.
Japanese users have Futae no Kiwami while English users have Falcon Punch.
Japanese users have Tetsu the Robot Pet Dog while English users have Give Pikachu a Face.
Japanese users have KabiKiller commercials while English users have Billy Mays.
Japanese users have X is Training while English users have Shrimp on a Treadmill.
Japanese users have Insane Set while English users have Nintendo 64 Kids.
Japanese users have Hissu Amoto San while English users have Rickroll.
Japanese users have Battle Dome while English users have CrossFire (not submitted).
And for the ultimate difference:
Japanese users have Train MADs and Touhou Project while English users have MLP: Friendship is Magic and Chuck Norris Facts.